Antibiotics and Obesity
February 26, 2018
The Question: Are children treated with long-term antibiotics at an increased risk of becoming obese?
The Study: In this study, 607 children aged two to seventy-one months old with urinary tract problems were either treated with the antibiotic trimethoprim-sulfamethoxazole (302) or a placebo (305) daily for two years to prevent urinary tract infections. All the children were weighed at six, twelve, eighteen, and twenty-four months after treatment was initiated.
The Results: The weight gain of the children in the two groups was similar. Further analysis of the results found no interaction between weight and age, sex, history of breast feeding, prior antibiotic use, adherence to study protocol, or development of urinary tract infections during the study.
Comment: The evidence is mounting that prolonged antibiotic use by children doesn’t result in increased risk of obesity.
Read More: JAMA Pediatrics, 02/17